Marty Friedman has been asked about the Megadeth solo in "Tornado of Souls" for thirty five years, and on VRP Rocks he gave the answer of somebody who has stopped pretending to understand it.
"I'm very, very pleased by that," he said. "And if you ask anybody who has one of those 'iconic' solos, at least for me and probably for the other guys, too, we're just trying to do the best we can at that moment. You never know what people are going to pick up on. If I hear it, I don't think it's anything better or more interesting than anything else I've done before or since."
Then he offered a theory, and it is the most interesting part. "It's long, and so many of these 'famous' solos seem to be long," he said, naming the Pink Floyd one, "Freebird", "Stairway To Heaven" and "Hotel California". Length, in his reading, is what makes an audience stop treating a solo as an interlude and start listening to it as a piece of music.
The same interview runs through Kiss as a teenage discovery, Cacophony with Jason Becker, the Ozzy Osbourne audition, Rust in Peace, why he left, and the Budokan reunion. He has played the song live again recently, which is presumably why he keeps being asked.